How Long Does Hydrocodone Stay in Your System? (2025 Guide)
Hydrocodone is a prescription opioid used for moderate to severe pain. Because of its potency and potential for dependence, many people want to know how long hydrocodone remains in the body and how long it can be detected on a drug test. This guide explains hydrocodone detection times, half life, and the factors that influence how long it stays in your system.
On average, hydrocodone stays in the system for 1 to 4 days. However, detection times vary depending on the type of test, dosage, metabolic rate, and how frequently the medication is used.
Hydrocodone Detection Times by Test Type
Below are general detection windows for hydrocodone and its metabolites:
| Test Type | Detection Window |
|---|---|
| Urine | 1 to 4 days |
| Blood | Up to 24 hours |
| Saliva | 1 to 2 days |
| Hair | Up to 90 days |
Some drug tests look for hydrocodone metabolites such as hydromorphone or norhydrocodone, which may remain detectable slightly longer.
Hydrocodone Half Life
Hydrocodone has an average half life of 3.5 to 9 hours, depending on the formulation and individual factors. This means half the drug is eliminated from the bloodstream within this time frame. Extended release formulations may remain detectable longer.
- Immediate-release hydrocodone: shorter half life
- Extended-release hydrocodone: longer duration and metabolism period
Factors That Influence Detection Time
Several variables affect how long hydrocodone stays in the system:
- Frequency of use – repeated use accumulates in the body
- Dosage strength
- Formulation (IR vs ER)
- Age and metabolism rate
- Liver and kidney health
- Hydration levels
- Body fat percentage
How Long Do the Effects of Hydrocodone Last?
The effects of hydrocodone depend on the formulation:
- Immediate-release: 4 to 6 hours
- Extended-release: up to 12 hours or longer
Common effects include slowed breathing, drowsiness, reduced pain, and impaired coordination.
Risks of Hydrocodone Misuse
Although hydrocodone is commonly prescribed, it has a high potential for dependence and misuse. Taking more than prescribed or using the medication without a prescription increases the risk of addiction and overdose.
- Respiratory depression
- Dependence or withdrawal symptoms
- Constipation
- Impaired coordination
- Increased tolerance
- Risk of overdose
Signs of Hydrocodone Misuse
- Using higher doses than prescribed
- Cravings or preoccupation with the medication
- Mood changes or irritability
- Doctor shopping or early refill requests
- Withdrawal symptoms when trying to stop
Related Educational Resources
- Codeine vs Hydrocodone: Key Differences
- How Long Oxycodone Stays in Your System
- 5 Types of Drug Addiction
- How Long Cocaine Stays in Urine
- How Long Crack Cocaine Stays in Urine
Treatment for Hydrocodone Addiction
If hydrocodone use is impacting your health, daily functioning, or relationships, treatment can help. The Heights Treatment Center provides structured, evidence-based programs designed to support adults through recovery in a compassionate, therapeutic environment.
Our treatment options include:
- Partial Hospitalization Program (PHP)
- Intensive Outpatient Program (IOP)
- Psychiatric care and medication management
- Cognitive Behavioral Therapy (CBT)
- Dialectical Behavior Therapy (DBT)
- Dual diagnosis treatment
If you or a loved one needs help, call (832) 979 3625 or visit The Heights Treatment to schedule a confidential assessment.
